Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | IFI27 |
| Gene Name: | IFI27 |
| Protein Full Name: | Interferon alpha-inducible protein 27, mitochondri |
| Alias: | Interferon-alpha-induced 11.5 kDa protein; Interferon-stimulated gene 12a protein; ISG12(a); p27 |
| Mass (Da): | 11268 |
| Number AA: | 119 |
| UniProt ID: | P40305 |
| Locus ID: | 3429 |
| COSMIC ID: | IFI27 |
| Gene location on chromosome: | 14q32.12 |
| Number of cancer specimens: | 7055 |
| Percent of cancer specimens with mutations: | 0.35 |
| Normal role description: | Mitochondrial membrane protein. Promotes cell death. Mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9. |