Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | RFX2 |
| Gene Name: | RFX2 |
| Protein Full Name: | DNA-binding protein RFX2 |
| Alias: | Dna binding protein rfx2; Flj14226; HLA class II regulatory factor RFX2; Regulatory factor X 2; Regulatory factor x, 2 (influences hla class ii expression); Regulatory factor x2; Regulatory factor x2 isoform a; Regulatory factor x2 isoform b; Rfx2; Rfx2 protein; Trans-acting regulatory factor 2 |
| Mass (Da): | 79969 |
| Number AA: | 723 |
| UniProt ID: | P48378 |
| Locus ID: | 5990 |
| COSMIC ID: | RFX2 |
| Gene location on chromosome: | 19p13.3-p13.2 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 19689 |
| Percent of cancer specimens with mutations: | 0.67 |
| Normal role description: | RXF2 is a transcription regulator of IL-5 receptor alpha subunit. |