Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | CCR9 |
| Gene Name: | CCR9 |
| Protein Full Name: | C-C chemokine receptor type 9 |
| Alias: | G-protein coupled receptor 28;GPR-9-6 |
| Mass (Da): | 42016 |
| Number AA: | 369 |
| UniProt ID: | P51686 |
| Locus ID: | 10803 |
| COSMIC ID: | CCR9 |
| Gene location on chromosome: | 3p21.31 |
| Cancer protein type: | OP |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | PROMOTES |
| Number of cancer specimens: | 20237 |
| Percent of cancer specimens with mutations: | 0.47 |
| Normal role description: | G-protein coupled receptor with specificity for the chemokine SCYA25/TECK: key role in leukocyte homing to gut mucosa. CCR9 is suggested to play a role in metastasis and invasion. |