Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | CCNH |
| Gene Name: | CCNH |
| Protein Full Name: | Cyclin-H |
| Alias: | CCNH; MO15-associated protein; p34; p37 |
| Mass (Da): | 37643 |
| Number AA: | 323 |
| UniProt ID: | P51946 |
| Locus ID: | 902 |
| COSMIC ID: | CCNH |
| Gene location on chromosome: | 5q14.3 |
| Number of cancer specimens: | 20018 |
| Percent of cancer specimens with mutations: | 0.27 |
| Normal role description: | Involved in cell cycle control by regulating CDK7 which is part of the CDK-activating kinase enzyme complex. However, it's expression and activity does not vary throughout the cell cycle. This enzyme complex also functions as a transcription factor for RNA polymerase II. |