Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: NEK4
Gene Name: NEK4
Protein Full Name: Serine/threonine-protein kinase Nek4
Alias: EC 2.7.11.1; Kinase Nek4; NIMA (never in mitosis gene a)-related kinase 4; NimA-related protein kinase 4; NRK2; Pp12301; Serine/threonine protein kinase 2; Serine/threonine protein kinase-2; STK2
Mass (Da): 94597
Number AA: 841
UniProt ID: P51957
Locus ID: 6787
COSMIC ID: NEK4
Gene location on chromosome: 3p21.1
Number of cancer specimens: 19854
Percent of cancer specimens with mutations: 0.47
Normal role description: NEK4 is a protein-serine/threonine kinase.


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