Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: MAPK10
Gene Name: MAPK10
Protein Full Name: Mitogen-activated protein kinase 10
Alias: C-Jun N-terminal kinase 3; EC 2.7.11.24; JNK3A; JNK3-alpha-2; Kinase JNK3; MAP kinase p49 3F12; MAPK10; MK10; P493F12; P54- beta; P54-beta; P54bSAPK; PRKM10; SAPK-beta; SERK2; Stress-activated protein kinase JNK3
Mass (Da): 52585
Number AA: 464
UniProt ID: P5377
Locus ID: 5602
COSMIC ID: MAPK10
Gene location on chromosome: 4q21-q23
Number of cancer specimens: 19536
Percent of cancer specimens with mutations: 0.54
Normal role description: MAPK10 is a protein-serine/threonine kinase.


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