Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: FGF8
Gene Name: FGF8
Protein Full Name: Fibroblast growth factor 8
Alias: Androgen-induced growth factor;Heparin-binding growth factor 8
Mass (Da): 26525
Number AA: 233
UniProt ID: P55075
Locus ID: 2253
COSMIC ID: FGF8
Gene location on chromosome: 10q24.32
Cancer protein type: OP
Effect of cancer mutation on protein: GAIN
Effect of active protein on cancer: PROMOTES
Number of cancer specimens: 20057
Percent of cancer specimens with mutations: 0.19
Normal role description: Mitogenic and cell survival activity


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