Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: FOXG1
Gene Name: FOXG1
Protein Full Name: Forkhead box protein G1
Alias: BF1; BF2; Brain factor 1; Brain factor 2; FKHL1; FKHL2; FKHL3; Forkhead box protein G1A; Forkhead box protein G1B; Forkhead box protein G1C; Forkhead-related protein FKHL1; Forkhead-related protein FKHL2; Forkhead-related protein FKHL3; HBF-2; HFK1; HFK2; HFK3; Transcription factor BF-1; Transcription factor BF-2
Mass (Da): 52352
Number AA: 489
UniProt ID: P55316
Locus ID: 2290
COSMIC ID: FOXG1
Gene location on chromosome: 14q13
Cancer protein type: UNCLEAR
Effect of cancer mutation on protein: UNCLEAR
Effect of active protein on cancer: UNCLEAR
Number of cancer specimens: 20151
Percent of cancer specimens with mutations: 0.84
Normal role description: Is a member of the forkhead transcription factor family. Suggested to play an important role in brain and telencephalon development. However the exact function is unknown.


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