Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: SOX10
Gene Name: SOX10
Protein Full Name: Transcription factor SOX-10
Mass (Da): 49911
Number AA: 466
UniProt ID: P56693
Locus ID: 6663
COSMIC ID: SOX10
Gene location on chromosome: 22q13.1
Cancer protein type: OP
Effect of cancer mutation on protein: UNCLEAR
Effect of active protein on cancer: UNCLEAR
Number of cancer specimens: 19787
Percent of cancer specimens with mutations: 0.47
Normal role description: Involved in self-renewal, Survival and maintaining of pluripotency of neural crest cells.


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