Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | PPP1CA |
| Gene Name: | PPP1CA |
| Protein Full Name: | Serine/threonine-protein phosphatase PP1-alpha cat |
| Alias: | EC 3.1.3.16; PP1A; PP-1A; PPP1A; Protein phosphatase 1, catalytic subunit, alpha isoform; Serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit; Serine/threonine protein phosphatase PP1-alpha 1, catalytic subunit |
| Mass (Da): | 37512 |
| Number AA: | 330 |
| UniProt ID: | P62136 |
| Locus ID: | 5499 |
| COSMIC ID: | PPP1CA |
| Gene location on chromosome: | 11q13.2 |
| Number of cancer specimens: | 20149 |
| Percent of cancer specimens with mutations: | 0.24 |
| Normal role description: | PPP1CA is a protein-serine/threonine phosphatase. |