Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | ARF6 |
| Gene Name: | ARF6 |
| Protein Full Name: | ADP-ribosylation factor 6 |
| Mass (Da): | 20082 |
| Number AA: | 175 |
| UniProt ID: | P62330 |
| Locus ID: | 382 |
| COSMIC ID: | ARF6 |
| Gene location on chromosome: | 14q21.3 |
| Number of cancer specimens: | 19718 |
| Percent of cancer specimens with mutations: | 0.11 |
| Normal role description: | GTP-binding protein, plays a role in vesicular trafficking, remodeling of membrane lipids, signalling pathways that lead to acting remodeling and as an activator of phospholipase D. And also stimulate the ADP-ribosyltransferase activity of thr cholera toxin. |