Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: ESRRG
Gene Name: ESRRG
Protein Full Name: Estrogen-related receptor gamma
Alias: ERR gamma-2; Estrogen receptor-related protein 3; Nuclear receptor subfamily 3 group B member 3
Mass (Da): 51306
Number AA: 458
UniProt ID: P62508
Locus ID: 2104
COSMIC ID: ESRRG
Gene location on chromosome: 1q41
Cancer protein type: OP
Effect of cancer mutation on protein: GAIN
Effect of active protein on cancer: PROMOTES
Number of cancer specimens: 19807
Percent of cancer specimens with mutations: 0.89
Normal role description: Working as a transcription factor it positively regulate transcription


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