Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | PAFAH1B2 |
| Gene Name: | PAFAH1B2 |
| Protein Full Name: | Platelet-activating factor acetylhydrolase IB subu |
| Alias: | PAF acetylhydrolase 30 kDa subunit; PAF-AH 30 kDa subunit; PAFAH subunit beta; PAF-AH subunit beta; PAFAHB; Platelet-activating factor acetylhydrolase, isoform Ib, subunit 2 (30kDa) |
| Mass (Da): | 25569 |
| Number AA: | 229 |
| UniProt ID: | P68402 |
| Locus ID: | 5049 |
| COSMIC ID: | PAFAH1B2 |
| Gene location on chromosome: | 11q23 |
| Number of cancer specimens: | 19783 |
| Percent of cancer specimens with mutations: | 0.01 |
| Commentary on involvement of protein in cancer: | Inactivates PAF by removing the acetyl group at the sn-2 position. This is a catalytic subunit. |