Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: PAFAH1B2
Gene Name: PAFAH1B2
Protein Full Name: Platelet-activating factor acetylhydrolase IB subu
Alias: PAF acetylhydrolase 30 kDa subunit; PAF-AH 30 kDa subunit; PAFAH subunit beta; PAF-AH subunit beta; PAFAHB; Platelet-activating factor acetylhydrolase, isoform Ib, subunit 2 (30kDa)
Mass (Da): 25569
Number AA: 229
UniProt ID: P68402
Locus ID: 5049
COSMIC ID: PAFAH1B2
Gene location on chromosome: 11q23
Number of cancer specimens: 19783
Percent of cancer specimens with mutations: 0.01
Commentary on involvement of protein in cancer: Inactivates PAF by removing the acetyl group at the sn-2 position. This is a catalytic subunit.


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