Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: DLG4
Gene Name: DLG4
Protein Full Name: Disks large homolog 4
Alias: Discs large 4; Discs, large 4; Postsynaptic density 95; Postsynaptic density protein 95; Presynaptic density protein 95; PSD95; SAP90; SAP-90; Synapse-associated protein 90
Mass (Da): 80495
Number AA: 724
UniProt ID: P78352; O14909
Locus ID: 1742
COSMIC ID: DLG4
Gene location on chromosome: 17p11.2; 17p13.1
Number of cancer specimens: 19557
Percent of cancer specimens with mutations: 0.55
General distribution of mutations: Only 2 sites


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