Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | IFITM3 |
| Gene Name: | IFITM3 |
| Protein Full Name: | Interferon-induced transmembrane protein 3 |
| Alias: | IFM3; INIB; Interferon-inducible protein 1-8U |
| Mass (Da): | 14632 |
| Number AA: | 133 |
| UniProt ID: | Q01628 |
| Locus ID: | 10410 |
| COSMIC ID: | IFITM3 |
| Gene location on chromosome: | 11p15.5 |
| Number of cancer specimens: | 19625 |
| Percent of cancer specimens with mutations: | 0.21 |
| Commentary on involvement of protein in cancer: | IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication. |