Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | MEF2B |
| Gene Name: | MEF2B |
| Protein Full Name: | Myocyte-specific enhancer factor 2B |
| Alias: | RSRFR2;Serum response factor-like protein 2 |
| Mass (Da): | 38639 |
| Number AA: | 365 |
| UniProt ID: | Q02080 |
| Locus ID: | 100271849 |
| COSMIC ID: | MEF2B |
| Gene location on chromosome: | 19p13.11 |
| Number of cancer specimens: | 19632 |
| Percent of cancer specimens with mutations: | 0.37 |
| Commentary on involvement of protein in cancer: | Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription. |