Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | NRG1 |
| Gene Name: | NRG1 |
| Protein Full Name: | Pro-neuregulin-1, membrane-bound isoform |
| Alias: | acetylcholine receptor-inducing activity; ARIA; breast cancer cell differentiation factor p45; GGF; GGF2; glial growth factor; heregulin; HGL; HRG; HRG1; HRGA; NDF; Neu differentiation factor; neuregulin 1; Neuregulin-1; Pro-NRG1; sensory and motor neuron-derived factor; SMDF |
| Mass (Da): | 70392 |
| Number AA: | 640 |
| UniProt ID: | Q02297 |
| Locus ID: | 3084 |
| COSMIC ID: | NRG1 |
| Gene location on chromosome: | 19p13.11 |
| Number of cancer specimens: | 20058 |
| Percent of cancer specimens with mutations: | 1.02 |
| Normal role description: | Ligand for ErbB2/ErbB3 receptors. |