Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: LGALS3BP
Gene Name: LGALS3BP
Protein Full Name: Galectin-3-binding protein
Alias: Basement membrane autoantigen p105;Lectin galactoside-binding soluble 3-binding protein;Mac-2-binding protein;Tumor-associated antigen 90K
Mass (Da): 65331
Number AA: 585
UniProt ID: Q08380
Locus ID: 3959
COSMIC ID: LGALS3BP
Gene location on chromosome: 17q25.3
Cancer protein type: UNCLEAR
Effect of cancer mutation on protein: UNCLEAR
Effect of active protein on cancer: UNCLEAR
Number of cancer specimens: 19625
Percent of cancer specimens with mutations: 0.41
Normal role description: Surface lectin binding protein. Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumour cells.


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