Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | PDE4D |
| Gene Name: | PDE4D |
| Protein Full Name: | cAMP-specific 3',5'-cyclic phosphodiesterase 4D |
| Alias: | cAMP-specific 3',5'-cyclic phosphodiesterase 4D: DPDE3: PDE43: cAMP-specific 3',5'-cyclic phosphodiesterase 4B: DPDE4: PDE32: cAMP-specific 3',5'-cyclic phosphodiesterase 4D: DPDE3: PDE43: cAMP-specific 3',5'-cyclic phosphodiesterase 4D: DPDE3: PDE43: cAMP-specific 3',5'-cyclic phosphodiesterase 4D: DPDE3: PDE43: cAMP-specific 3',5'-cyclic phosphodiesterase 4D: DPDE3: PDE43: cAMP-specific 3',5'-cyclic phosphodiesterase 4D: DPDE3: PDE43: cAMP-specific 3',5'-cyclic phosphodiesterase 4D: DPDE3: PDE43: cAMP-specific 3',5'-cyclic phosphodiesterase 4D: DPDE3: PDE43: cAMP-specific 3',5'-cyclic phosphodiesterase 4B: DPDE4: PDE32: Phosphodiesterase 4B, cAMP-specific (Phosphodiesterase E4 dunce homolog, Drosophila); cAMP-specific 3',5'-cyclic phosphodiesterase 4D: DPDE3: PDE43: cAMP-specific 3',5'-cyclic phosphodiesterase 4D: DPDE3: PDE43: cAMP-specific 3',5'-cyclic phosphodiesterase 4D: DPDE3: PDE43: cAMP-specific 3',5'-cyclic phosphodiesterase 4D: DPDE3: PDE43: cAMP-specific 3',5'-cyclic phosphodiesterase 4D: DPDE3: PDE43: cAMP-specific 3',5'-cyclic phosphodiesterase 4D: DPDE3: PDE43: cAMP-specific 3',5'-cyclic phosphodiesterase 4D: DPDE3: PDE43: cAMP-specific 3',5'-cyclic phosphodiesterase 4D: DPDE3: PDE43 |
| Mass (Da): | 91115 |
| Number AA: | 809 |
| UniProt ID: | Q08499 |
| Locus ID: | 5144 |
| COSMIC ID: | PDE4D |
| Gene location on chromosome: | 5q12 |
| Number of cancer specimens: | 19717 |
| Percent of cancer specimens with mutations: | 0.45 |
| Commentary on involvement of protein in cancer: | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. |