Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | MAP4K2 |
| Gene Name: | MAP4K2 |
| Protein Full Name: | Mitogen-activated protein kinase kinase kinase kin |
| Alias: | B lymphocyte serine/threonine-protein kinase; BL44; EC 2.7.11.1; GCK; Germinal center kinase; Kinase GCK; M4K2; M4K2_HUMAN; MAPK/ERK kinase kinase kinase 2; MEK kinase kinase 2; MEKKK 2; MEKKK2; Rab8 interacting protein; RAB8IP |
| Mass (Da): | 91556 |
| Number AA: | 820 |
| UniProt ID: | Q9Y4K4 |
| Locus ID: | 5871 |
| COSMIC ID: | MAP4K2 |
| Gene location on chromosome: | 11q13.1 |
| Number of cancer specimens: | 19549 |
| Percent of cancer specimens with mutations: | 0.5 |
| Normal role description: | MAP4K2 is a protein-serine/threonine kinase. |