Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: FLII
Gene Name: FLII
Protein Full Name: Protein flightless-1 homolog
Alias: FLI; Fli1; Flightless I; Flightless I homologue variant; Flightless-I protein homolog; FLIH; FLIL; MGC39265
Mass (Da): 144751
Number AA: 1269
UniProt ID: Q13045
Locus ID: 2314
COSMIC ID: FLII
Gene location on chromosome: 17p11.2
Cancer protein type: UNCLEAR
Effect of cancer mutation on protein: UNCLEAR
Effect of active protein on cancer: UNCLEAR
Number of cancer specimens: 19625
Percent of cancer specimens with mutations: 0.86
Normal role description: May be involved in estrogen signalling, ebryonic development and cell migration. May act as coactivator in transcription activation.


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