Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: MAP2K5
Gene Name: MAP2K5
Protein Full Name: Dual specificity mitogen-activated protein kinase
Alias: CXA1; EC 2.7.12.2; HsT17454; Kinase MEK5; MAP kinase kinase 5; MAP2K5; MAPK,ERK kinase 5; MAPK/ERK kinase 5; MAPKK 5; MAPKK5; Mitogen-activated protein kinase kinase 5; MKK5; MP2K5; PRKMK5
Mass (Da): 50112
Number AA: 448
UniProt ID: Q13163
Locus ID: 5607
COSMIC ID: MAP2K5
Gene location on chromosome: 15q23
Cancer protein type: NA
Effect of cancer mutation on protein: NA
Effect of active protein on cancer: NA
Number of cancer specimens: 19556
Percent of cancer specimens with mutations: 0.36
Normal role description: NA


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