Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | TCIRG1 |
| Gene Name: | TCIRG1 |
| Protein Full Name: | V-type proton ATPase 116 kDa subunit a isoform 3 |
| Alias: | A3; Atp6i; Atp6n1c; Atp6v0a3; Oc116; Oc-116kda; Optb1; Stv1; T-cell, immune regulator 1; T-cell, immune regulator 1 isoform a; T-cell, immune regulator 1 isoform b; T-cell, immune regulator 1, Atpase, h+ transporting, lysosomal v0 subunit a3; Tcirg1; Tirc7; Tirc7 protein; Vph1; Vpp3 |
| Mass (Da): | 92998 |
| Number AA: | 830 |
| UniProt ID: | Q13488 |
| Locus ID: | 10312 |
| COSMIC ID: | TCIRG1 |
| Gene location on chromosome: | 11q13.2 |
| Number of cancer specimens: | 19717 |
| Percent of cancer specimens with mutations: | 0.48 |
| Normal role description: | Channel membrane protein - ATPase. Part of the proton channel of V-ATPases. Seems to be directly involved in T-cell activation. |