Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | FGFBP1 |
| Gene Name: | FGFBP1 |
| Protein Full Name: | Fibroblast growth factor-binding protein 1 |
| Alias: | 17 kDa heparin-binding growth factor-binding protein |
| Mass (Da): | 26264 |
| Number AA: | 234 |
| UniProt ID: | Q14512 |
| Locus ID: | 9982 |
| COSMIC ID: | FGFBP1 |
| Gene location on chromosome: | 4p15.32 |
| Number of cancer specimens: | 19625 |
| Percent of cancer specimens with mutations: | 0.28 |
| Commentary on involvement of protein in cancer: | Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth. |