Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | COL19A1 |
| Gene Name: | COL19A1 |
| Protein Full Name: | Collagen alpha-1(XIX) chain |
| Alias: | COJA1; COL9A1L; collagen alpha-1; collagen, type XIX, alpha 1 |
| Mass (Da): | 115220 |
| Number AA: | 1142 |
| UniProt ID: | Q14993 |
| Locus ID: | 1310 |
| COSMIC ID: | COL19A1 |
| Gene location on chromosome: | 6q12-q13 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 19688 |
| Percent of cancer specimens with mutations: | 1.82 |
| Normal role description: | COL19A1 encodes for the alpha chain of a type XIX collagen. May connect fibrils and other extracellular matrix molecules. Suggested to be involved in development of the esophagus and skeletal myogenesis. |