Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | CCDC85B |
| Gene Name: | CCDC85B |
| Protein Full Name: | Coiled-coil domain-containing protein 85B |
| Alias: | Hepatitis delta antigen-interacting protein A |
| Mass (Da): | 22091 |
| Number AA: | 202 |
| UniProt ID: | Q15834 |
| Locus ID: | 11007 |
| COSMIC ID: | CCDC85B |
| Gene location on chromosome: | 11q12.1 |
| Number of cancer specimens: | 19625 |
| Percent of cancer specimens with mutations: | 0.04 |
| Commentary on involvement of protein in cancer: | Functions as a transcriptional repressor. May inhibit the activity of CTNNB1 in a TP53-dependent manner and thus regulate cell growth. May function in adipocyte differentiation, negatively regulating mitotic clonal expansion. |