Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | IGFBP7 |
| Gene Name: | IGFBP7 |
| Protein Full Name: | Insulin-like growth factor-binding protein 7 |
| Alias: | IGFBP-rP1;MAC25 protein;PGI2-stimulating factor;Prostacyclin-stimulating factor;Tumor-derived adhesion factor |
| Mass (Da): | 29130 |
| Number AA: | 282 |
| UniProt ID: | Q16270 |
| Locus ID: | 3490 |
| COSMIC ID: | IGFBP7 |
| Gene location on chromosome: | 4q12 |
| Number of cancer specimens: | 20057 |
| Percent of cancer specimens with mutations: | 0.18 |
| Normal role description: | Secreted growth factor binding protein. Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. |