Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | CA9 |
| Gene Name: | CA9 |
| Protein Full Name: | Carbonic anhydrase 9 |
| Alias: | CAH9; CAIX; CA-IX; Carbonate dehydratase IX; Carbonic anhydrase 9; Carbonic anhydrase IX; Carbonic dehydratase; EC 4.2.1.1; G250; Membrane MN; MN; P54/58N; RCC-associated G250; RCC-associated protein G250; Renal cell carcinoma-associated G250 |
| Mass (Da): | 49698 |
| Number AA: | 459 |
| UniProt ID: | Q16790 |
| Locus ID: | 768 |
| COSMIC ID: | CA9 |
| Gene location on chromosome: | 9p13.3 |
| Number of cancer specimens: | 19625 |
| Percent of cancer specimens with mutations: | 0.42 |
| Normal role description: | Catalyze reversible hydration of carbon dioxide. Participate in respiration, calcification, acid base balance, bone resorption, formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. |