Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | DUSP7 |
| Gene Name: | DUSP7 |
| Protein Full Name: | Dual specificity protein phosphatase 7 |
| Alias: | Dual specificity protein phosphatase PYST2; DUS7; DUS7_HUMAN; EC 3.1.3.16; EC 3.1.3.48; PYST2 |
| Mass (Da): | 40551 |
| Number AA: | 368 |
| UniProt ID: | Q16829 |
| Locus ID: | 1849 |
| COSMIC ID: | DUSP7 |
| Gene location on chromosome: | 3p21 |
| Number of cancer specimens: | 20149 |
| Percent of cancer specimens with mutations: | 0.27 |
| Commentary on involvement of protein in cancer: | Regulates the activity of the MAP kinase family in response to changes in the cellular environment. PYST2-S may act as a negative regulator of PYST2-L although it is unclear whether this is by competing for transcription, translation or activation factors. |