Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: CRTC2
Gene Name: CRTC2
Protein Full Name: CREB-regulated transcription coactivator 2
Alias: CREB regulated transcription coactivator 2; TORC2; Transducer of regulated cAMP response element-binding protein 2; Transducer of regulated CREB protein 2
Mass (Da): 73302
Number AA: 693
UniProt ID: Q53ET0
Locus ID: 200186
COSMIC ID: CRTC2
Gene location on chromosome: 1q21.3
Number of cancer specimens: 19717
Percent of cancer specimens with mutations: 0.56
Normal role description: Promotes the transcription of genes targeted by the c-AMP response element-binding protein


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