Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | ZNF569 |
| Gene Name: | ZNF569 |
| Protein Full Name: | Zinc finger protein 569 |
| Alias: | Zap1; Zn569; Znf; Znf569 |
| Mass (Da): | 79583 |
| Number AA: | 686 |
| UniProt ID: | Q5MCW4 |
| Locus ID: | 148266 |
| COSMIC ID: | ZNF569 |
| Gene location on chromosome: | 19q13.12 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 19688 |
| Percent of cancer specimens with mutations: | 0.84 |
| Normal role description: | Relatively uncharacterized protein; however, it does have a high degree of squence identity with the Krueppel C2H2-type zinc-finger protein family -- implicating its role as a transcription protein. Mutations in this gene have been found in breast tumours. |
| Commentary on involvement of protein in cancer: | May be involved in transcriptional regulation |