Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | DNAJB4 |
| Gene Name: | DNAJB4 |
| Protein Full Name: | DnaJ homologue subfamily B member 4 |
| Alias: | DJB4; DnaJ (Hsp40), subfamily B, member 4; DnaJ homolog subfamily B member 4; DNAJW; DNJB4; Heat shock 40 kDa protein 1 homolog; Heat shock protein 40 homolog; HLJ1; HSP40 homolog |
| Mass (Da): | 37807 |
| Number AA: | 337 |
| UniProt ID: | Q6DKZ0 |
| Locus ID: | 11080 |
| COSMIC ID: | DNAJB4 |
| Gene location on chromosome: | 1p31.1 |
| Number of cancer specimens: | 19718 |
| Percent of cancer specimens with mutations: | 0.25 |
| Commentary on involvement of protein in cancer: | Probable chaperone. Homodimer. The C-terminal section interacts with the C-terminal tail of OPRM1. Interacts also with SDIM1. |