Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | GADD45B |
| Gene Name: | GADD45B |
| Protein Full Name: | Growth arrest and DNA damage-inducible protein GAD |
| Alias: | Myeloid differentiation primary response protein MyD118;Negative growth regulatory protein MyD118 |
| Mass (Da): | 17818 |
| Number AA: | 160 |
| UniProt ID: | Q6IX74 |
| Locus ID: | 4616 |
| COSMIC ID: | GADD45B |
| Gene location on chromosome: | 19p13.3 |
| Number of cancer specimens: | 19625 |
| Percent of cancer specimens with mutations: | 0.09 |
| Commentary on involvement of protein in cancer: | Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK. |