Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | ATAD2 |
| Gene Name: | ATAD2 |
| Protein Full Name: | ATPase family AAA domain-containing protein 2 |
| Alias: | ANCCA; ATPase family, AAA domain containing 2; DKFZp667N1320; EC 3.6.1.3; FLJ39814; MGC29843; MGC5254; PRO2000 |
| Mass (Da): | 158554 |
| Number AA: | 1390 |
| UniProt ID: | Q6PL18 |
| Locus ID: | 29028 |
| COSMIC ID: | ATAD2 |
| Gene location on chromosome: | 8q24.13 |
| Number of cancer specimens: | 19626 |
| Percent of cancer specimens with mutations: | 1.23 |
| Normal role description: | May be transcriptional coactivator of nuclear receptor ESR1. May regualte the expression of a subset of estradiole target genes such as CCND1, MYC and E2F1 by interacting with ESR1. |