Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: IDO2
Gene Name: IDO2
Protein Full Name: Indoleamine 2,3-dioxygenase 2
Alias: Indoleamine 2,3-dioxygenase-like protein 1;Indoleamine-pyrrole 2,3-dioxygenase-like protein 1
Mass (Da): 45424
Number AA: 407
UniProt ID: Q6ZQW0
Locus ID: 169355
COSMIC ID: IDO2
Gene location on chromosome: 8p11.21
Number of cancer specimens: 19557
Percent of cancer specimens with mutations: 0.42
Commentary on involvement of protein in cancer: Catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan catabolism


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