Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: SULF2
Gene Name: SULF2
Protein Full Name: Extracellular sulfatase Sulf-2
Alias: extracellular sulfatase Sulf-2; HSULF-2; KIAA1247; SULF-2; sulfatase 2
Mass (Da): 100450
Number AA: 870
UniProt ID: Q81WU5
Locus ID: 55959
COSMIC ID: SULF2
Gene location on chromosome: 20q12-q13.2
Cancer protein type: UNCLEAR
Effect of cancer mutation on protein: UNCLEAR
Effect of active protein on cancer: UNCLEAR
Number of cancer specimens: 19782
Percent of cancer specimens with mutations: 1.04
Normal role description: SULF2 acts as a coreceptor for numerous heparin-binding growth factors and cytokines and are involved in cell signalling.


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