Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: MARCH3
Gene Name: MARCH3
Protein Full Name: E3 ubiquitin-protein ligase MARCH3
Alias: E3 ubiquitin-protein ligase MARCH3; EC 6.3.2.-; MARCH-III; MARH3; Membrane-associated ring finger (C3HC4) 3; Membrane-associated RING-CH protein III; MGC48332; RING finger protein 173; RNF173
Mass (Da): 28504
Number AA: 253
UniProt ID: Q86UD3
Locus ID: 115123
COSMIC ID: MARCH3
Gene location on chromosome: 5q23.2
Cancer protein type: UNCLEAR
Effect of cancer mutation on protein: UNCLEAR
Effect of active protein on cancer: UNCLEAR
Number of cancer specimens: 19603
Percent of cancer specimens with mutations: 0.19


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