Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: KRT73
Gene Name: KRT73
Protein Full Name: Keratin, type II cytoskeletal 73
Alias: K2C73; Keratin 6 irs3; Keratin 73; KRT6IRS3
Mass (Da): 58923
Number AA: 540
UniProt ID: Q86Y46
Locus ID: 319101
COSMIC ID: KRT73
Gene location on chromosome: 12q13.3
Cancer protein type: UNCLEAR
Effect of cancer mutation on protein: UNCLEAR
Effect of active protein on cancer: UNCLEAR
Number of cancer specimens: 19688
Percent of cancer specimens with mutations: 0.94
Normal role description: A component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle. Involved in hair formation.


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