Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | ZDHHC13 |
| Gene Name: | ZDHHC13 |
| Protein Full Name: | Palmitoyltransferase ZDHHC13 |
| Alias: | DHHC-13; FLJ10852; FLJ10941; HIP14L; HIP14-related protein; Huntingtin-interacting protein 14 related protein; Huntingtin-interacting protein HIP3RP; MAPK-activating protein PM03; NF-kappa-B-activating protein 209; Palmitoyltransferase ZDHHC13; ZDH13; Zinc finger DHHC domain-containing protein 13; Zinc finger, DHHC-type containing 13 |
| Mass (Da): | 70889 |
| Number AA: | 622 |
| UniProt ID: | Q8IUH4 |
| Locus ID: | 54503 |
| COSMIC ID: | ZDHHC13 |
| Gene location on chromosome: | 11p15.1 |
| Number of cancer specimens: | 19625 |
| Percent of cancer specimens with mutations: | 0.25 |
| Commentary on involvement of protein in cancer: | Palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, DLG4/PSD95, GAD2, SYT1 and HD. May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane. Has transforming activity. Mediates Mg2+ transport. |