Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: NAV1
Gene Name: NAV1
Protein Full Name: Neuron navigator 1
Alias: DKFZp781D0314; FLJ12560; FLJ14203; H1; KIAA1151; MGC14961; Neuron navigator-1; POMFIL3; Pore membrane and/or filament interacting like protein 3; Pore membrane and/or filament-interacting-like protein 3; Steerin-1; Unc-53 homolog 1; Unc53H1
Mass (Da): 202472
Number AA: 1877
UniProt ID: Q8NEY1
Locus ID: 89796
COSMIC ID: NAV1
Gene location on chromosome: 1q32.3
Cancer protein type: UNCLEAR
Effect of cancer mutation on protein: UNCLEAR
Effect of active protein on cancer: UNCLEAR
Number of cancer specimens: 19718
Percent of cancer specimens with mutations: 1.24
Normal role description: Function unknown. Suggested to play a role in in neuronal development and regeneration.


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