Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | CAGE1 |
| Gene Name: | CAGE1 |
| Protein Full Name: | Cancer-associated gene 1 protein |
| Alias: | CAGE-1; Cancer/testis antigen 3; CTAG3 |
| Mass (Da): | 90250 |
| Number AA: | 777 |
| UniProt ID: | Q8TC20 |
| Locus ID: | 285782 |
| COSMIC ID: | CAGE1 |
| Gene location on chromosome: | 6p24.3 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 19557 |
| Percent of cancer specimens with mutations: | 0.5 |
| Normal role description: | CAGE1 is a nuclear localized protein. In normal tissue CAGE1 expression is restricted to the testis while high levels of expression can be detected in cancer tissues. The exact function of CAGE1 in the cell is still relatively unknown. It has been shown to be expressed in lung, cervix and stomach cancers and may be associated with tumour progression. |