Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: LEO1
Gene Name: LEO1
Protein Full Name: RNA polymerase-associated protein LEO1
Alias: Leo1, Paf1/RNA polymerase II complex component,; RDL; Replicative senescence downregulated leo1-like protein; Replicative senescence down-regulated leo1-like protein
Mass (Da): 75404
Number AA: 666
UniProt ID: Q8WVC0
Locus ID: 123169
COSMIC ID: LEO1
Gene location on chromosome: 15q21.2
Number of cancer specimens: 19603
Percent of cancer specimens with mutations: 0.39


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