Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | BAALC |
| Gene Name: | BAALC |
| Protein Full Name: | Brain and acute leukemia cytoplasmic protein |
| Mass (Da): | 19224 |
| Number AA: | 180 |
| UniProt ID: | Q8WXS3 |
| Locus ID: | 79870 |
| COSMIC ID: | BAALC |
| Gene location on chromosome: | 8q22.3 |
| Cancer protein type: | OP |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | PROMOTES |
| Number of cancer specimens: | 19812 |
| Percent of cancer specimens with mutations: | 0.15 |
| Normal role description: | BAALC is a cytoplasmic localized protein expressed primarily in hematopoeitic and nervous tissues tissues. This protein may have a function in promoting cellular adhesion and motility in neuroectodermal and hematopoietic cells. Overexpression of this protein has been implicated in acute myeloid leukemias. |