Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | PHF16 |
| Gene Name: | PHF16 |
| Protein Full Name: | Protein Jade-3 |
| Alias: | JADE3; KIAA0215; PHD finger protein 16 |
| Mass (Da): | 93808 |
| Number AA: | 823 |
| UniProt ID: | Q92613 |
| Locus ID: | 9767 |
| COSMIC ID: | PHF16 |
| Gene location on chromosome: | Xp11.23 |
| Number of cancer specimens: | 19625 |
| Percent of cancer specimens with mutations: | 0.57 |
| Commentary on involvement of protein in cancer: | Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. |