Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: RAD54L
Gene Name: RAD54L
Protein Full Name: DNA repair and recombination protein RAD54-like
Alias: HHR54; HR54; RAD54; RAD54 homolog; RAD54A; RAD54-like
Mass (Da): 84352
Number AA: 747
UniProt ID: Q92698
Locus ID: 8438
COSMIC ID: RAD54L
Gene location on chromosome: 1p34.1
Cancer protein type: TSP
Effect of cancer mutation on protein: LOSS
Effect of active protein on cancer: PROMOTES
Number of cancer specimens: 19720
Percent of cancer specimens with mutations: 0.48
Normal role description: Involved in homologous recombination and repair of DNA.


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