Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: TNR
Gene Name: TNR
Protein Full Name: Tenascin-R
Alias: Janusin; Restrictin; Restrictin, janusin; Tenascin R; Tenascin-R; TN-R
Mass (Da): 149548
Number AA: 1358
UniProt ID: Q92752
Locus ID: 7143
COSMIC ID: TNR
Gene location on chromosome: 1q25.1
Cancer protein type: UNCLEAR
Effect of cancer mutation on protein: UNCLEAR
Effect of active protein on cancer: UNCLEAR
Number of cancer specimens: 19812
Percent of cancer specimens with mutations: 2.85
Normal role description: TNR is a neural extracellular matrix protein involved in neuronal development and differentiation. Different interactions with cells and matrix components modulate neuronal growth.


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