Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: FGF14
Gene Name: FGF14
Protein Full Name: Fibroblast growth factor 14
Alias: FGF-14; FHF4; FHF-4; Fibroblast growth factor homologous factor 4; SCA27
Mass (Da): 27702
Number AA: 247
UniProt ID: Q92915
Locus ID: 2259
COSMIC ID: FGF14
Gene location on chromosome: 13q33.1
Cancer protein type: OP
Effect of cancer mutation on protein: GAIN
Effect of active protein on cancer: PROMOTES
Number of cancer specimens: 20120
Percent of cancer specimens with mutations: 0.35
Normal role description: Mitogenic and cell survival activities, involved in various biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumour growth and invasion.


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