Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | WNT2B |
| Gene Name: | WNT2B |
| Protein Full Name: | Protein Wnt-2b |
| Alias: | Wingless-type MMTV integration site family, member 2B; WNT13; Wnt-13 |
| Mass (Da): | 43770 |
| Number AA: | 391 |
| UniProt ID: | Q93097 |
| Locus ID: | 7482 |
| COSMIC ID: | WNT2B |
| Gene location on chromosome: | 1p13 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 20057 |
| Percent of cancer specimens with mutations: | 0.42 |
| Normal role description: | WNTB2 is a member of the wingless-type MMTV integration site (WNT) family. This family of proteins plays a regulatory role in a variety of developmental processes, including: of cell growth and differentiation. Mutations in this gene have been observed in ovarian tumors. |