Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | ARL11 |
| Gene Name: | ARL11 |
| Protein Full Name: | ADP-ribosylation factor-like protein 11 |
| Alias: | ADP-ribosylation factor-like 11; ARLTS1; FLJ33930 |
| Mass (Da): | 21390 |
| Number AA: | 196 |
| UniProt ID: | Q969Q4 |
| Locus ID: | 15761 |
| COSMIC ID: | ARL11 |
| Gene location on chromosome: | 13q14.2 |
| Number of cancer specimens: | 19625 |
| Percent of cancer specimens with mutations: | 0.21 |
| Commentary on involvement of protein in cancer: | May play a role in apoptosis. May act as a tumor suppressor. Expressed in lung and leukocytes. Defects in ARL11 may be a cause of susceptibility to chronic lymphocytic leukemia (CLL) |