Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | RAD51AP1 |
| Gene Name: | RAD51AP1 |
| Protein Full Name: | RAD51-associated protein 1 |
| Alias: | PIR51; R51A1; RAD51 associated protein 1; RAD51-interacting protein |
| Mass (Da): | 38457 |
| Number AA: | 352 |
| UniProt ID: | Q96B01 |
| Locus ID: | 10635 |
| COSMIC ID: | RAD51AP1 |
| Gene location on chromosome: | 12p13.2-p13.1 |
| Number of cancer specimens: | 19718 |
| Percent of cancer specimens with mutations: | 0.26 |
| Commentary on involvement of protein in cancer: | May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA. |